1/18/08

(D)

Lesson Unit/Topic

• Introduce unit conversions.

Practice worksheets.

1/23/08

(F;1:10)

Lesson Unit/Topic

• Microarray in SNP analysis.

'Microarrays in diagnosis' worksheet.

1/25/08

(B)

Lesson Unit/Topic

• Follow-up on the Microarray-SNP family diagnosis.

Analysis write-up is due next class.

1/29/08

(D)

Lesson Unit/Topic

• Introduce Electrophoresis and pipetman use..

• Class will work on Pipetting activity.

Review Micropipetting notes in binder.

1/31/08

(F)

Lesson Unit/Topic

• Finish discussing pedigrees.

• Quiz

Work on pedigree analysis - pages 26 and 27.

Review gel electrophoresis by watching the following online tutorial.

Have a nice weekend!

2/4/08

(B)

Lesson Unit/Topic

• Electrophoresis learning cycle.

Finish questions on Electrophoresis worksheet - pages 20-23 (both DNA and RNA are negatively charged but since RNA is single-stranded as opposed to DNA which is double-stranded - RNA will move faster compared to DNA).

Quiz next class on Conversions and Pedigrees and Microarrays.

2/6/08

(D; Paraliturgy)

Lesson Unit/Topic

• Quiz

• Finish analyzing Electrophoresis.

 Come prepared for upcoming test review.

2/8/08

(F)

Lesson Unit/Topic

• Review for test next class.

Study for the Test on Electrophoresis, Conversions, Micropipetting and Pedigrees and Microarrays.

Here are the answers to the remaining pedigree worksheets.

2/12/08

(B; Class Mtg)

Lesson Unit/Topic

• TEST.

Research the medical problems handed out in class.

2/14/08

(D)

Lesson Unit/Topic

• Introduce Family with genetic disorder.

• Discuss OMIM.

Class uses OMIM to research genetic disorder.

Have a good Break!

2/25/08

(F)

Lesson Unit/Topic

• Research the clinical symptoms that were handed out in class today.

Predict father's genotype (from the test) - remember that the disorder is X-linked recessive.

Finish researching the symptoms.

2/27/08

(B; Noon)

Lesson Unit/Topic

• Class presents a brief explanation of the clinical symptoms for each family member.

Review the symptoms discussed today.

Romanov mystery assignment is due next class.

2/29/08

(D)

Lesson Unit/Topic

• Finish discussing clinical symptoms.

• Analyze symptoms to finalized the relevant ones.

Use OMIM to make a tentative diagnosis for the genetic disorder.

A family pedigree with the genotypes, pattern of inheritance and affected gene locus is due next class (must be typed).

Have a good weekend!.

3/4/08

(F)

Lesson Unit/Topic

• Describe the 'Central Dogma'.

Review class-notes and finish the worksheet on pages 52-53 for homework.

3/6/08

(B)

Lesson Unit/Topic

• Class uses online module to learn about the history behind the Double-Helix.

Review class-notes, study the online module to review replication.

3/10/08

(D)

Lesson Unit/Topic

• Discuss Transcription & RNA editing.

• Online activity to review the discovery of  the "Double Helix".

Finish worksheet and review class-notes.

3/12/08

(F)

Lesson Unit/Topic

• Describe Translation and the Genetic code.

Class reviews notes and come prepared for the quiz next class on "Central Dogma'.

3/14/08

(B)

Lesson Unit/Topic

• Quiz.

• Review Replication.

Study for test on Central Dogma, Romanov mystery and online module worksheets. Have a nice weekend!

3/18/08

(D)

Lesson Unit/Topic

• Test.

Finish page 69 in your Binder and review class-notes on PCR.

Happy Easter!

3/20/08

(F; Noon)

Lesson Unit/Topic

• Class works on 'Gene therapy' webquest.

Finish answering questions on the first page of the webquest.

3/25/08

(B; Grades Close)

Lesson Unit/Topic

• Class sets up PCR.

• 'Gene therapy' webquest continued.

Finish answering questions on the first page of the webquest.

3/27/08

(D)

Lesson Unit/Topic

• Class analyzes PCR results by electrophoresis.

• 'Gene therapy' webquest continued.

Work on your PCR lab report.

3/31/08

(F)

Lesson Unit/Topic

• Introduce Mitochondrial DNA PCR.

• Review 'Gene Therapy' webquest.

PCR lab report due next class.

Click here for Gel image.

Quiz next class on PCR.

Protocol flowchart for the Mitochondrial PCR experiment is also due next class.

Have a good week!

4/2/08

(B)

Lesson Unit/Topic

• Class sets up 'Mitochondrial DNA PCR'.

Study for PCR quiz next class.

4/4/08

(D; First Friday)

Lesson Unit/Topic

• Case study on PCR in Forensics.

Review notes and come prepared for the class review.

4/8/08

(F)

Lesson Unit/Topic

• Review for test on 'PCR'.

• Class analyses mt. DNA PCR samples

Study for the Test on PCR - general and mitochondrial DNA PCR, Gene therapy, STRs (Case study).

4/10/08

(B)

Lesson Unit/Topic

• Test.

http://www.dnai.org/b/index.html

Review Restriction enzymes from this module - take notes as you go along.

Here's what you need for the lab report - conclusion, Gel 1 and Gel2.

Lab report is due on 4/25/08.

4/21/08

(D)

Lesson Unit/Topic

• Introduce Restriction Enzymes.

Review class-notes and finish the restriction digest started in class.

4/23/08

(F; Health Day)

Lesson Unit/Topic

• Discuss restriction analysis.

Work on assigned problems - pages 86, 87 and 88 in your binder.

Mt. DNA PCR lab report is due next class.

4/25/08

(B)

Lesson Unit/Topic

• Class sets up restriction digest.

• Review restriction analysis problem.

Review your PCR test and bring it with you next class.

Finish the restriction analysis problems on page 88 and then work on the challenge problem in the class worksheet.

 Have a nice weekend!

4/29/08

(D)

Lesson Unit/Topic

• Continue reviewing Restriction analysis problems.

Quiz on restriction analysis next class.

5/1/08

(F; Liturgy)

Lesson Unit/Topic

• Quiz on restriction  analysis.

.

5/5/08

(B)

Lesson Unit/Topic

• Introduce DNA sequencing.

• Discuss Manual sequencing.

Review the process of  manual sequencing

and take notes.

Read pages 96-97 in your binder and finish pages 98 and 99 in the binder.

5/7/08

(D)

Lesson Unit/Topic

• Class sets up PCR for Cycle sequencing.

Review the process of  cycle sequencing

and take notes.

Finish the sequencing activity that was started in class -- design a 5 base primer, write out the fragments and draw the gel.

5/9/08

(F)

Lesson Unit/Topic

• Class purifies the PCR product.

 Work on the sequencing problem.

5/13/08

(B)

Lesson Unit/Topic

• Class loads samples on the DNA sequencer.

Work on your Restriction Digest lab report.

Gel picture for the lab report.

5/15/08

(D)

Lesson Unit/Topic

• Review sequencing

.

5/20/08

(F)

Lesson Unit/Topic

• Test on Restriction enzymes & DNA sequencing.

.

5/22/08

(B)

Lesson Unit/Topic

.

5/27/08

(D)

Lesson Unit/Topic

.

5/29/08

(F)

Lesson Unit/Topic

.

Lesson Unit/Topic

Prepare for Final Exam